Abstract |
The radioimmunoassay of TSH (human thyrotropin) was
performed by utilizing anti-h-TSH antibody and purified
human thyrotropin supplied from Daiichi from Jan. 1978
through Aug. 1980 the serum concentration of TSH was
measured on 41 cases with various thyroid diseases, and
22 normal persons. Among 41 cases, 9(22%) were primary
hypothyroitlism, 17(41%) Graves' disease, 8(20%)
subacute or chronic lymphocytic thyroiditis, and 7(17%)
nodular goiter. The results were as follows:1) The
normal values of serum TSH in 22 cases of control group
were 4.2±1.7μU/ml, (1.9∼7.4μU/ml), which were
within normal range in kit used in this study. 2) The
serum TSH concentration in 9 cases with primary
hypoehroidism were 97.1±116.4μU/ml(14. 0∼300μU/ml),
which were significantly elevated as compared, with
normal control values. 3) The serum TSH concentration
in 17 cases with Graves' disease were
1.5±0.6μU/ml(1.0∼2.5μU/ml), which were below than
normal control. 4) The serum TSH concentration in 8
cases with subacute or chronic lymphocytic thyroiditis
revealed wide ranges(1.6∼220μU/ml), according to the
state of thyroid function. 5) The serum TSH values in 7
cases with nodular goiters were 2.3±2.0μU/ml, which
were strictly within normal levels. 6) The serum TSH
levels were elevated during prolonged treatment with
Tapazole(Methimazole) without serial check of the serum
TSH concentration in Graves' disease, so the serial
measurement of serum TSH concentration was considered
of available index of thyroid states.
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