대한핵의학회지 (1967년~2009년)
대한핵의학회지 1981;15(1)37~7
Organification 장애에 의한 선천성 갑상선기능저하병과 Huerthle 세포선종이 병발된 1예 ( A Case of Congenital Hypothyroidism Due to Organification Defect Associated wth Huerthle Cell Adenoma )
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Author 김병태(Byung Tae Kim),이기상(Kee Sang Lee),정순일(Soon Il Chung),김삼용(Sam Yong Kim),조경삼(Kyung Sam Cho),조보연(Bo Yeon Cho),고창순(Chang Soon Koh),
Affiliation
Abstract

Cogenital hypothyroidism due to organification defect was first reported by Haddad and Sidbury in 1959. The organification defect is easily proved by perchlorate discharge test. We experienced a patient who had large goiter, growth and mental retardation, and revealed positive reponse to perchlorate discharges test, and the surgical biopsied specimen showed Huerthle cell adenoma, which was probably due to chronic stimulation of thyroid stimulating hormone, or coexisted incidentally. Described here a case of congenital hypothyroidism due to organification defect associated with Huerthle cell adenoma, with review of some literatures.

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