방사면역측정에서 방사성 동위원소 표식법 개발에 관한 연구 - 제1편. Human Thyrotropin 의 온화한 조건하 125I-표지를 위한 새로운 방법 - ( A Study on Radiolabelling Method in Radioimmunoassay - Part 1. A New Method for the 125I-Labelling of Human Thyrotropin u () |
Author |
서정헌(Jung Hun Suh),조보연(Bo Yeon Cho),박영자(Yong Ja Park),김병국(Byong Kook Kim),고창순(Chang Soon Koh), |
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Abstract |
125I-Labelling of human thyrotropin (h-TSH) Was performed
using a small amount of chloramine T(CT) as an oxidant at
room temperature. When compared with the conventional
method that uses a large amount of CT, this method
facilitated uniform labelling and reduced the damage of
h-TSH by CT, a strong oxidizing reagent. h-TSH* prepared
by the new method was comparable to the commercial
product of Daiichi Company, in terms of affinity to
antibody and effective period. |
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Full text Article |
28500067.pdf
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