알쯔하이머형의 노인성 치매에서 99mTc-HMPAO 뇌 SPECT 를 이용한 뇌혈류분포의 특성 ( Analysis of Regional Cerebral Blood Flow Using 99mTc-HMPAO Brain SPECT in Senile Dementia of Alzheimer Type )
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고창순(Chang Soon Koh),이명철(Myung Chul Lee),이명혜(Myung Hae Lee),노재규(Jae Kyu Roh),우종인(Chong In Woo), |
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| Abstract |
Tc-99m-HMPAO brain SPECT studies were performed in 11 patients with Alzheimer's disease, 7 patients with psychological depression and 12 normal controls. Changes of regional cerebral blood flow was semiquantitatively analyzed and the results were as follows. 1) In 11 patients with Alzheimer's disease, significant reduction of regional cerebral blood flow was found In both temporoparietal areas. 2) Relative perfusion between cerebral hemispheres was rather symmetrical in patient with Alzheimer's disease. 3) All patients with depression showed normal SPECT findings. As for conclusion, Tc-99m-HMPAO brain SPECT seemed to be a valuable method for clinical assessment and management of patients with Alzheimer's disease. |
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