대한핵의학회지 (1967년~2009년)
대한핵의학회지 1991;25(1)87~8
원저 : 강직성 척추염에서 99mTc - MDP 골스캔의 임상적 의의 ( Clinical Significance of Bone Scan with 99mTc - MDP in Ankylosing Spondylitis )
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Author 김덕윤(Deog Yoon Kim),김상은(Sang Eun Kim),이동수(Dong Soo Lee),정준기(June Key Chung),이명철(Myung Chul Lee),조보연(Bo Youn Cho),고창순(Chang Soon Koh),강흥식(Heung Sik Kang),
Affiliation
Abstract

To evaluat.e the diagnostic usefulness of quantitative sacroiliac joint scintigraphy and its clinica1 significance in the ankylosing spondylitis, we measured SIS ratio (Sacroiliac Joint/Sacrum Uptake ratio) by region of interest method in 52 patients with ankylosing spondylitis. As compared with radiological grade, SIS ratio was significantly elevated in the eariy stage of ankylosing spondylitis and returned to normal range in the late stage. Scintigraphic finding of focaI cptakes of radiotracer at multiple spinal apophyseal joints was charactnistic and proximal large joints were niore involved than distaI joints. The incidence and extent of the arthropathy revealed by scnitigraphy exceeded that which was clinically evident, and scintigraphy was more sensitive to detect syrnptomatic lesion than radiography. Therefore, it is suggested that bone scan is useful for the early diagnosis and the assessment of clinical activity of involved joints of ankylosing spondylitis.

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