원저 : Thallium - 201 심근 단층영상의 정량적 분석 ( Quantitative Analysis of Thallium - 201 Myocardial Tomograms ) () |
Author |
김상은(Sang Eun Kim),남기병(Gi Byoung Nam),최창운(Chang Woon Choi),최기준(Kee Joon Choi),이동수(Dong Soo Lee),손대원(Dae Won Sohn),안규리(Cu Rie Ahn),정준기(June Key Chung),이명묵(Myoung Mook Lee),이명철(Myung Chul Lee),박영배,최윤식,서정돈,이영우,고창순, |
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Abstract |
The purpose of this study was to assess the ability of
quantitative Tl-201 tomography to identify and localize
coronary artery disease (CAD). The study population
consisted of 4l. patients (31 males, 10 females; mean
age 55 +- 7 yr) including 14 with prior myocardial
infarction who underwent both exercise Tl-201
myocardium SPECT and coronary angiography for the
evaluation of chest pain. From the short axis and
vertical long axis tomograms, stress extent polar maps
were generated by Cedars-Sinai Medical Center prograrn,
and the 9 stress defect extent (SDE) was quantified for
each coronary artery territory. For the purpose of this
study, the coronary circulation was divided into 6
arterial segments, and the myocardial ischemic score
(MIS) was calculated from the coronary angiogram.
Sensitivity for the detection of CAD (>50% coronary
stenosis by angiography) by stress eXtent polar map was
95% in single vessel disease, and 100% in double and
triple vessel deseases. Overall sensitivity was 97%<.
Sensitivity and specificity for the detection of
individual diseased vessels werc, respectively, 87% and
90% for the left anterior descending artery (LAD), 36%
and 93% for the left circumflex artery (LCX), and 71%
and 70%, for the right coronary artery (RCA).
Concordance for the detection of individual diseased
vessels between the coronary angiography and stress
polar map was fair for the LAD (kappa=0.70), and RCA
(kappa=0.41) lesions, whereas it was poor for the LCK
lesions (kappa =0.32) There were siginificant
correlations between the MIS and SDE in LAD (rs=0. 56,
p=0.0027), and RCA territory (rs=0.60, p=0.0094). No
significant correlation was found in LCX territory.
When total vascular territories were combined, there
was a significant correlation between the MIS and SDE
(rs=0.42, p=0,0116). In conclusion, the quantitative
analysis of TI-201 tomograms appears to be accurate for
determining the presence and location of CAD. |
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Full text Article |
28501129.pdf
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