원저 : 관상동맥질환에서 휴식기 심전도게이트혈액풀스캔을 이용한 각종 심기능 지표들의 평가 및 ROC 분석 ( Evaluation of Various Cardiac Indices and ROC Analysis in Coronary Artery Disease Employing Resting ECG Gated Blood Pool Scan ) () |
Author |
최창운(Chang Woon Choi),이동수(Dong Soo Lee),김상은(Sang Eun Kim),정준기(June Key Chung),이명철(Myung Chul Lee),박영배(Young Bae Park),서정돈(Jung Don Seo),이영우(Young Woo Lee),고창순(Chang Soon Koh), |
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Abstract |
Gated blood pool scan is frequently used for evaluating
the change in cardiac function in various cardiac
diseases. But resting gated blood pool scan using only
LVEF as a cardiac index has been consitently shown to
have a low sensitivity, which is about 50%, in
detecting coronary artery disease. So it is recommended
to compare exercise gated blood pool scan to resting
gated blood pool scan. Exercise tests, however, are not
always possible, especially in patients with
musculoskeletal diseases, recent myocardial infarction
and in elderly persons. We studied the usefulness of
resting gated blood pool scan using multiple indices in
evaluating the patients with coronary artery disease.
Studied cases were 185 patients with coronary artery
disease (angina pectoris 31, myocardial infarction 154)
and 25 normals with low likelihood of coronary artery
disease. We used Tc-90m-labeled RBC, 740 MBq labeled by
in vivo method. The data were evaluated by Micro DELTA
computer program. The results were as following: 1) The
ejection rates (PER, AER) and filling rates (PFR, AFR)
were different in normals and patients with angina
pectoris or myocardial infarction. 2) Mean phase angie,
ejection rates and filling rates could separate normals
from coronary artery disease patients with normal LVEF.
3) Regional ejection fraction was decreased at the site
of the infarct in patients with myocardial infarction.
4) Peak filling rate was the most detectable index in
evaluation of cardiac function in patients with
coronary artery disease. 5) The threshold at 1.5
standard deviation of normal range was considered as
the most reliable cut-off value from ROC analysis.
These data suggest that the resting gated blood pool
scan has an important role in the evaluation of cardiac
functional changes using various cardiac indices in
patients with coronary artery disease. |
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Full text Article |
28501154.pdf
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