대한핵의학회지 (1967년~2009년)
대한핵의학회지 1992;26(2)244~7
원저 : 간질증후군의 99mTc - HMPAO Brain SPECT ; Ictal Study ( 99mTc - HMPAO Brain SPECT in Medically Intractable Epilepsy ; Ictal Study )
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Author 정태섭(Tae Sub Chung),서정호(Jung Ho Suh),김동익(Dong Ik Kim),이종두(Jong Doo Lee),박창윤(Chang Yun Park),홍용국(Yong Kook Hong),이병인(Byung In Lee),허균(Kyun Huh),
Affiliation
Abstract

Both interictal and ictal Tc-99m-HMPAO brain SPECT were performed in 22 patients with medically intractable epilepsy. Localization of epileptic foci in our patients was made by combined results of EEG and other tests, including Wada test, magnetic resonance imaging, and neuropsy- chometric test. Among them, ictal Tc-99m- HMPAO SPECT, localized epilptic foci in 20 of 22 patients and provided evidence of epileptic focus in 12 patients by demonstrating maximally increased regional cerebral perfusion (rCP) in epileptic foci during the ictal study with decreased rCP in interictal study. Ictal Tc-99m-HMPAO SPECT Was particularly useful for investigating epileptic foci, and when correlated with simultaneously recorded ictal EEG, provided further insight for localizing epileptic foci. Conclusively, Tc-99m-HMPAO SPECT is a useful, noninvasive method of localizing epileptic activity which may be particularly important for presurgical investigations, especially in those patients without large morphological lesions.

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