원저 : 소아 폐쇄성 요로질환에서 이뇨 신 신티그라피의 정량적 분석 ( Quantitative Assessment of Obstructive Uropathy with Diuretic Renography in children ) () |
Author |
김종호(Jong Ho Kim),이동수(Dong Soo Lee),곽철은(Cheol Eun Kwark),이경한(Kyung Han Lee),최창운(Chang Woon Choi),정준기(June Key Chung),이명철(Myung Chul Lee),고창순(Chang Soon Koh),최용(Yong Choi),최황(Hwang Choi), |
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Affiliation |
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Abstract |
Differentiating the various causes of hydronephrosis
from that of obstruction can be very difficult. The
decision-marking process for those instances of urinary
tract dilatation that require surgical correction and
those that do not is based in part on the findings of
diuresis renography. The methodology for performing
this test has differed among nuclear medicine
practitioners and the surgical findings are
occasionally discrepant from the diuretic renogram
interpretation. Consequently we made an automatic
computer software program that calculates the slope of
the response curve. The quantitative indices, such as
the injection and response t1/2 by linear-fitting and
monoexponential-fitting, were compared with the visual
assessment of the diuretic cinerenography and clinical
outcome in 50 children (62 kidneys) with ureteropelvic
junction obstruction. Pooled diuresis renogram data
indicated that: (1) Visual evaluation of the diuretic
cinerenography is a sensitive (87%, 54/62) tool to
differentiate obstruction in suspected ureteropelvic
junction obstruction. (2) The cut-off value (maximum
washout t1/2 with non- obstruction) of injection and
response t1/2 by linear-fitting were 40 min. (3) The
sensitivity and specificity using injection and
response t1/2 by linear-fitting for obstruction were
89%(23/26) and 100%(30/30), respectively. (4) Response
t1/2 as well as injection t1/2 by monoexponential-
fitting do not stratify children with possible
ureteropelivic junction obstruction. In conclusion,
quantitative assessment of diuretic renography as well
as visual assessment of diuretic cinerenography
correlate well with surgical and clinical outcome of
suspected ureteropelvic junction obstruction. |
Keyword |
Diuretic renography, Quantitation |
Full text Article |
28501308.pdf
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