대한핵의학회지 (1967년~2009년)
대한핵의학회지 1994;28(3)307~6
원저 : 난천성 측두엽간질의 발작간 뇌혈류 SPECT , MRI 와 수술성과 비교 ( Interictal rCBF SPECT , MRI and Surgical Outcome of Intractable Temporal Lobe Epilepsy )
()
Author 전석길 , 주양구 , 이상도 , 손은익 , 이영환 ( Seok Kil Zeon , Yang Goo Joo , Sang Doe Lee , Eun Ik Son , Young Hwan Lee ),
Affiliation
Abstract

Interictal single photon emission computed tomography of regional cerebral blood flow (rCBF SPECT) in 18 intractable temporal lobe epilepsy patient,s(8 male and 10 female patients : average 23.5 years old) were eompared with 2.0 T magnetic resanance imaging (MRI). And surgical outcome was analysed with the findings, symptom duration and lateralization of temporal lobe. Preoperatively rCRF SPKCT was done in all 18 patients with intravenous injection of 740 MRq 99mTc HMPAO. MRI was also done preoperatively in 13 patients, Surgical outcome was classified by Engels outcome classification (four part classification recommended at the first Palm Desert conference). rCRF SPECT detected correctly lateralising abnormality of temporal lobe hypoperfusion in 13/ 18(72.2%), contralateral temporal lobe hypoperfusion in 2/18(11.1%) and showed no definite abnormality in 3/18(16.7%). The positive predictive value of unilateral temporal lobe hypoperfusion was 87%. MRI detected correct localising abnormality in 8/13(61.5%), such as hippocampal atrophy(7/13), asymmetric temporal horn(6/13), anterior t,emporal lobe atrophy(1/13), increased signal intensity from hippocampus(1/13) and ealcific density(3/13), and no abnormal finding was noted in 5/13(38.5%), There was no false positive findings and the positive predictive value of MRI was 100%, Only 2 cases showed same lateralization findings in rCBF SPECT and MRI. There was no significant correlation between symptom duration and no abnormal findings on SPECT or MRI. Surgical outcome showed elass 1 in 15/18(83.3%), and class II in 2/18(11.1%). One case of no abnormal finding in both SPECT and MRI showed elass I1I surgical outcome. No class IV surgical out.come was noted. Surgical outcome, lat.eralization of epileptic focus in temporal lobe and abnormal findings in rCBR SPECT or MRI were not significantly correlated.

Keyword Temporal lobe epilepsy. rCBF SPECT, MRI, Surgery
Full text Article 28501392.pdf 28501392.pdf
(03121)서울시 종로구 지봉로 29 금호팔레스빌딩 1705호
TEL : 02-745-2040 FAX : 02-745-3833 E-mail : ksnm@ksnm.or.kr
Copyright 2012 by The Korean Society of Nuclear Medicine(KSNM)