대한핵의학회지 (1967년~2009년)
대한핵의학회지 1995;29(1)31~10
원저 : 휴식 / 부하 심근 Rubidium - 82 양전자단층촬영과 부하 / 휴식 심근 Tc - 99m - MIBI 단일광자단층촬영의 비교 ( Stress / Rest Tc - 99m - MIBI SPECT in Comparison with Rest / Stress Rubidium - 82 PET )
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Author 이동수(D . S . Lee),강건욱(K . W . Kang),이경한(K . H . Lee),정재민(J . M . Jeong),곽철은(C . Kwark),정준기(J . K . Chung),이명철(M . C . Lee),서정돈(J . D . Seo),고창순(C . S . Koh),
Affiliation
Abstract

We compared stress/rest myocardial Tc-99m-MIBI tomographic image findings with rest/stress rubidium-82 tomographic images. In 23 patients with coronary artery disease (12 of them received bypass grafts before) and 6 normal subjects, rest rubidium PET study was performed, rubidium-82 and Tc-99m-MrBI were injected simultaneously to each patient after dipyridamole stress for rubidium PET and MIBI SPECT; and rest MIBI SPECT was performed 4 hours thereafter. We scored segmental decrease of rubidium, or MIBI uptakes into 5 grades for 29 segments from 3 short-axis, vertical and horizontal slices. Scores were summed for each major arterial territory. When more score than two grade-2's or one grade-3 was considered as the cue for significant stenosis for major arterial territories, 67% of 46 stenosed arteries were found with MIBI studies and 78% of them by rubidium studies. Fourteen among 28 grafted arterial territories of 12 post-CABG patients were found normal with both rubidium and MIBI. Segmental scores were concordant between rubidium and MIBI in 72% of 709-stress segments and in 80% of 825 rest segments. Stress rubidium segmental scores were less than stress MIBI scores in 9%, so were rest rubidium scores. Stress rubidium scores were more than stress MIBI scores in 20% of segments, and rest rubidium segmental scores were more than rest MIBI scores in 11%. Rank correlations (Spearman's rho's more than 0.7(stress) and 0.5(rest), slopes (MIBI/rubidium) around 0.7(stress) and 0.9(rest) suggested deeper and wider defects in stress with rubidium. Slope over 1 (MIBI/rubidium) with LAD segemental scores at rest and 7 territories which had much larger score with MIBI revealed exaggeration of rest defects with rest MIBI in same-day stress/rest study. Difference scores (stress- rest for each territory) suggesting ischemia were larger with rubidium (slope of MIBI/rubidium around 0.45). As has been implied by animal or separate-day- human studies, these segmental analyses with simultaneous examination in patients told that rubi

Keyword Tc-99m-MIBI SPECT, Rb-82 PET, Dipyridamole stress, Segmental analysis
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