원저 : 측두엽 간질에성 발작기 뇌관류 SPECT의 간질병소 국소화 성능 ( The Performance of Ictal Brain SPECT for Localizing Epileptogenic Foci in Temporal Lobe epilepsies ) () |
Author |
김은실(Eun Sil Kim),이동수(Dong Soo Lee),정준기(June Key Chung),이명철(Myung Chul Lee),고창순(Chang Soon Koh),장기현(Kee Hyun Chang),이상건(Sang Kun Lee),정천기(Chun Kee Chung), |
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Affiliation |
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Abstract |
Anterior temporal lobectomy has become a widely used
resective surgery in patients with medically
intractable temporal lobe epilepsies. Prerequisites of
this resection include the accurate localization of the
epileptogenic focus and the determination that the
proposed resection would not result in unacceptable
postoperative memory or language deficits. The purpose
of this study was to evaluate the performance of ictal
SPECT compared to MRI findings for localization of
epiletogenic foci in this group of patients. 11
patients who had been anterior temporal oral lobectomy
were evaluated with ictal 99m-Tc-HMPAO SPECT and MRI.
MRI showed 8/11(73%) concordant lesion to the side of
surgery and ictal SPECT also showed 8/11(73%)
concordant hyperperfusion. In 3 cases with incorrect or
nonlocalizing findings of MRI, ictal SPECT showed
concordant hyperperfusion. In 2 cases confirmed by pre-
resectional invasive EEG, MRI showed bilateral and
contralateral lesion but ictal SPECT showed concordant
hyperperfusion. 3 delayed injection of ictal SPECT
showed discordant hyperperfusion. Thus, ictal SPECT was
a useful method for localizing epileptogenic foci in
temporal lobe epilepsies and appeared complementay to
MRI. |
Keyword |
Temporal lobe epilepsies, Ictal 99mTc- HMPAO SPECT, MRI |
Full text Article |
28501539.pdf
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