Author |
정수교(Soo Kyo Chung),김성훈(Sung Hoon Kim),백준현(Joon Hyun Baik),김영주(Young Joo Kim),천경아(Kyung Ah Chun),박석희(Seog Hee Park),박용휘(Yong Whee Bahk),신경섭(Kyung Sub Shin), |
Abstract |
It is well known that hepatobiliary agent are taken up
by metastatic hepatocellular carcinoma(HCC) as well as
primary HCC. But the reported cases of the extrahepatic
metastasis of HCC diagnosed by hepatobiliary
scintigraphy are for the most part hematogenous ones.
The relation of the uptake pattern of hepatobiliary
agent in the primary and metastatic HCC is also still
remains unknown. So we undertook this study to evaluate
the relation of the hepatobiliary scintigraphic
patterns of primary and metastatic HCC with different
metastiatic routes. Nine patients with primary HCC and
twelve cases of metastaic HCC including four lung
metastases, one bone metastasis, one right atrial
metastasis, one peritoneal wall metastasis, and five
lymph node metastases were studied with Tc-99m-DISIDA
scintigraphy. The images were taken on 10, 30 minutes,
1, 2, 4-6 hours. The overall detection rates of
hematogenous metastases(lung and bone) is 60%(3 of 5),
direct metastasis(right atrium and peritoneal wall),
100%(2 of 2) and lymphatic metastases, 0%(0 of 5). In
four of five metastatic cases demonstrated with
hepatobiliary scintigraphy, biliary agent is also taken
up by primary HCC lesions. And the appearing time of
the radioactivity in the direct metastatic HCC lesion
is same as that of primary HCC and in the cases of
hematogenous metastasis, earlier than that of primary
HCC. Hepatobiliary scintigraphy is more useful in the
diagnosis of the metastatic HCC than primary HCC, in
the cases of hematogenous and direct metastasis. |