원저 : 부하-휴식 1일 영상법을 이용한 심근관류 SPECT 에서 99mTc-tetrofosmin 과 99mTc-MIBI 의 관동맥질환 진단율 비교 ( Comparison of 99mTc-tetrofosmin and 99mTc-sestamibi Myocardial Perfusion SPECT in Detecting Coronary Artery Fisease ) () |
Author |
민정준(Jung Jun Min),범희승(Hee Seung Bom),송호천(Ho Cheon Song),정환정(Hwan Jeoung Jeoung),김지열(Ji Yeul Kim), |
|
Affiliation |
|
Abstract |
Purpose: Tc-99m-tetrofosmin(TF) is a recently proposed
myocardial imaging agent which has similar biokinetic
characteristics to Tc-99m-sestamibi(MIBI). The aim of
this study was to compare TF and MIBI myocardial
perfusion SPECTs in detecting coronary artery disease.
Materials and Methods: One hundred and sixty
patients(l0l males, 59 females, mean age 57±9 yr) who
had undergone both myocardial perfusion SPECT (M-
SPECT) and coronary angiography within 1 month were
studied. M-SPECT was performed using TF in 115 patients
and MIBI in 45 patients. Stress-rest one day protocol
was used in all patients A coronary stenosis was
considered significant when the luminal diameter ≥50%
was compromised. The chi square test was used to
compare, differences in sensitivity and specificity
between the two groups. Results: There was no
difference in age and diseased coronary artery branches
between the two groups. There were more male patients
in TF group: Male-to-female ratios of TF and MIBI
groups were 78:37 and 23:22, respectively (p〈0.05).
The overall sensitivity of TF study was 92% and
specificity 36%. The overall, sensitivity and
specificity of MIBI study were 93% and 30%
respectively. There was no difference between TF and
MIBI groups in identifying individual diseased coronary
artery branches. Conclusion: One day stress-rest
myocardial SPECT using either TF or MIBI was comparable
and was a very sensitive test in detecting coronary
artery disease. |
Keyword |
99mTc-tetrofosmin, 99mTc-sestamibi , coronary artery disease, SPECT |
Full text Article |
28502127.pdf
|
|
|