운동 정도와 무고나한 Tc-99m Methoxyisobuty1 Isonitrile 심근관류 스캔의 진단능 (Diagnostic Ability of Tc-99m MIBI SPECT in Coronary Artery Diseases is not Affected by the Degree of Exercise ) () |
Author |
이재태(Jaetae Lee),김종수(Jong Soo Kim),천경아(Kyung Ah Chun),이상우(Sang Woo Lee),강동영(Do Young Kang),조용근(Yong Keun Cho),채성철(Shung Chull Chae),이규보(Kyu Bo Lee), |
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Affiliation |
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Abstract |
Purpose: The sensitivity of ST-depression in the
electrocardiogram during exercise is influenced by the
level of efforts. However, unlike the prevalence of ST-
depression on exercise ECG, the degree of exercise is
reported to do not influence the diagnostic ability of
myocardial perfusion scan. Furthermore, the relation
between the prevalence of myocardial ischemia and
effort is still controversial. We evaluated the effect
of the degree of exercise on the ability of SPECT
imaging to detect coronary artery stenosis. Materials
and Methods: The patient population was comprised of
111 patients (73 men and 38 women, mean age 56 years)
who underwent an exercise test in conjunction with Tc-
99m MIBI and cardiac catheterization within 3 months
apart each other. The degree of exercies was classified
into four groups according to the percentage of maximal
predicted heart rate. The sensitivity and specificity
was compared between each group. Results: The overall
diagnostic sensitivity was significantly higher with
Tc-99m MIBI SPECT than exercise ECG. The specificity
was not significantly different between two tests.
Sensitivity and specificity of Tc-99m MIBI was not
different between four groups. Sensitivity for
individual coronary stenosis seemed to be lower in
subjects who had premature termination of exercise due
to early appearance of ST depression. Conclusion: These
results suggest that the overall diagnostic sensitivity
of Tc-99m MIBI myocardial perfusion SPECT is not
significantly affected by the degree of exercise in
stable patients undergoing symptom-limited treadmill
exercise testing. Myocardial perfusion SPECT imaging
should be added to routine exercise stress testing for
the detection of coronary artery disease. |
Keyword |
Exercise, Tc-99m MIBI, Myocardium, Perfusion, SPECT, Coronary artery disease, Diagnosis |
Full text Article |
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