게이트 방법과 감쇠보정이 심근 관류 SPECT 의 관상동맥질환 진단 성능에 미치는 영향 ( Influence of Gating and Attenuation-correction for Diagnostic Performance of Usual Rest/stress Myocardial Perfusion SPECT in Coronary Artery Disease ) () |
Author |
이동수(Dong Soo Lee),여정석(Jeong Seok Yeo),소영(Young So),천기정(Gi Jeong Cheon.),김경민(Kyeong Min Kim),정준기(June Key Chung),이명철(Myung Chul Lee), |
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Affiliation |
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Abstract |
Purpose: Either gated myocardial perfusion SPECT or
attenuation corrected SPECT can be used to improve
specificity in the diagnosis of coronary artery
disease. We investigated in this study whether gating
or attenuation correction improved diagnostic
performance of rest/stress perfusion SPECT in patients
having intermediate pre-test likelihood of coronary
artery disease. Materials and Methods: Sixty-eight
patients underwent rest attenuation-corrected T1-
20l/dipyridamole stress gated attenuation-corrected Tc-
99m-MIBI SPECT using an ADAC vertex camera (M:F=29:39,
aged 59±12 years, coronary artery stenosis≥70%. one
vessel: 13, two vessel: 18, three vessel: 8, normal:
29). Using a five-point scale, three physicians graded
the post-test likelihood of coronary artery disease for
each arterial territory (1 normal, 2: possibly normal
3:equivocal, 4: possibly abnormal, 5: abnormal).
Sensitivity, specificity and area under receiver-
operating-characteristic curves were compared for each
operator between three methods: (A) non-attenuation-
corrected SPECT; (B) gated SPECT added to (A); and (C)
attenuation-corrected SPECT added to (B). Results: When
grade 3 was used as the criteria for coronary artery
disease, no differences in sensitivity and specificity
were found between the three methods for each operator
Areas under receiver- operating-characteristic curves
for diagnosis of coronary artery disease revealed no
differences between each modality (p>005). Conclusion:
In patients at intermediate risk of coronary artery
disease, gated SPECT and attenuation-corrected SPECT
did not improve diagnostic performance. |
Keyword |
Coronary arteriosclerosis, Tc-99m MIBI, ROC curve, SPECT, Gated myocardial SPECT |
Full text Article |
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