후두엽간질 환자에서 F-18-FDG PET 와 발작기 Tc-99m-HMPAO SPECT 의 간질원인병소 진단 성능 비교 ( Comparison of Diagnostic Performance between Interictal F-18-FDG PET and Ictal Tc-99m-HMPAO SPECT in Occipital Lobe Epilepsy ) () |
Author |
김석기(Seok Ki Kim),이동수(Dong Soo Lee),여정석(Jeong Seok Yeo),이상건(Sang Kun Lee),김주용(Joo Yong Kim),정재민(Jae Min Jeong),정준기(June Key Chung),이명철(Myung Chul Lee), |
|
Affiliation |
|
Abstract |
Purpose: Interictal F-18-fluorodeoxyglucose (FDG) PET
and ictal Tc-99m-HMPAO SPECT are found to be useful in
localizing epileptogenic zones in neocortical lateral
temporal or frontal lobe epilepsy. We investigated
whether interictal F-18-FDG PET or ictal Tc-99m-HMPAO
SPECT was useful to find epileptogenic zones in
occipital lobe epilepsy (OLE). Materials and Methods:
We reviewed patterns of hypometabolism in interictal F-
18-FDG PET and of hyperperfusion in ictal Tc-99m-HMPAO
SPECT in 17 OLE patients (mean age=27¡¾6.8 year,
M:F=10:7, injection time=30¡¾17 sec). OLE was
diagnosed based on invasive electroencephalography
(EEG) study, surgery and post-surgical outcome (Engel
class I in all for average 14 months). Results:
Epileptogenic zones were correctly localized in 9 (60%)
out of 15 patients by interictal F-18-FDG PET.
Epiletogenic hemispheres were correctly lateralized in
14 patients (93%). By ictal Tc-99m-HMPAO SPECT,
epileptogenic hemispheres were correctly lateralized in
13 patients (76%), but localization was possible only
in 3 patients (18%). Among patients who showed no
abnormality with MR imaging and no correct localization
with ictal Tc-99m-HMPAO SPECT, interictal F-18-FDG PET
was helpful in 2 patients. Conclusion: Ictal Tc-99m-
HMPAO SPECT was helpful in lateralization but not in
localization in OLE. Interictal F-18-FDG PET was
helpful for localization of epileptogenic zones even in
patients with ambiguous MR or ictal SPECT findings. Key
KW: Occipital lobe epilepsy, Tc-99m-HMPAO, Ictal
perfusion SPECT, F-18-FDG, PET, SPECT |
Keyword |
Occipital lobe epilepsy, Tc-99m-HMPAO, Ictal perfusion SPECT, F-18-FDG, PET, SPECT |
Full text Article |
28502402.pdf
|
|
|