대한핵의학회지 (1967년~2009년)
대한핵의학회지 2003;37(5)325~330
전신성 홍반성 루푸스에서 F-18 FDG PET상 기저핵 포도당대사 증가 소견을 보이는 무도병 1예
(Chorea in Systemic Lupus Erythematosus: Evidence for Bilateral Putaminal Hypermetabolism on F-18 FDG PET)
Author 서욱장,정선미,고수진,이창근,김재승,임주혁,유빈,문희범,
Wook Jang Seo, M.D.1, Son Mi Chung, M.D., Su-Jin Koh, M.D., Chang-Keun Lee, M.D.,Jae Seung Kim, M.D., Joo-Hyuk Im, M.D., Bin Yoo, M.D., and Hee-Bom Moon, M.D.
Affiliation 울산대학교 의과대학 서울아산병원 내과, 핵의학과, 신경과
Department of Internal Medicine, Nuclear Medicine and Neurology Universitiy of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Abstract

We describe a 54-year-old woman with systemic lupus erythematosus (SLE) who suddenly presented with chorea and had positive antiphospholipid antibodies. F-18 FDG PET showed abnormally increased glucose metabolism in bilateral putamen and primary motor cotex. Tc-99m ECD SPECT also showed abnormally increased regional cerebral blood flow in bilateral putamen. She was treated with corticosteroid and aspirin after which the symptoms improved. Four months later, follow up F-18 FDG PET showed improvement with resolution of hypermetabolism in bilateral putamen. This case suggests that striatal hypermetabolism is associated with chorea in SLE.

Keyword Systemic lupus erythematosus, Chorea, F-18 FDG, PET
Full text Article file_37_05.pdf file_37_05.pdf
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