전신성 홍반성 루푸스에서 F-18 FDG PET상 기저핵 포도당대사 증가 소견을 보이는 무도병 1예 (Chorea in Systemic Lupus Erythematosus: Evidence for Bilateral Putaminal Hypermetabolism on F-18 FDG PET) |
Author |
서욱장,정선미,고수진,이창근,김재승,임주혁,유빈,문희범, |
Wook Jang Seo, M.D.1, Son Mi Chung, M.D., Su-Jin Koh, M.D., Chang-Keun Lee, M.D.,Jae Seung Kim, M.D., Joo-Hyuk Im, M.D., Bin Yoo, M.D., and Hee-Bom Moon, M.D. |
Affiliation |
울산대학교 의과대학 서울아산병원 내과, 핵의학과, 신경과 Department of Internal Medicine, Nuclear Medicine and Neurology Universitiy of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea |
Abstract |
We describe a 54-year-old woman with systemic lupus
erythematosus (SLE) who suddenly
presented with chorea and had positive antiphospholipid
antibodies. F-18 FDG PET showed abnormally
increased glucose metabolism in bilateral putamen and
primary motor cotex. Tc-99m ECD SPECT also
showed abnormally increased regional cerebral blood
flow in bilateral putamen. She was treated with
corticosteroid and aspirin after which the symptoms
improved. Four months later, follow up F-18 FDG PET
showed improvement with resolution of hypermetabolism
in bilateral putamen. This case suggests that
striatal hypermetabolism is associated with chorea in
SLE. |
Keyword |
Systemic lupus erythematosus, Chorea, F-18 FDG, PET |
Full text Article |
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