MR조영제와 분자영상 (MR Contrast Agents and Molecular Imaging) |
Author |
문우경, |
Woo Kyung Moon, M.D. |
Affiliation |
서울대학교 의과대학 방사선과학교실 Department of Radiology, College of Medicine, Seoul National University, Seoul, Korea |
Abstract |
The two major classes of magnetic resonance (MR) contrast agents are paramagnetic contrast agents, usually
based on chelates of gadolinium generating T1 positive signal enhancement, and super-paramagnetic contrast
agents that use mono- or polycrystalline iron oxide to generate strong T2 negative contrast in MR images. These
paramagnetic or super-paramagnetic complexes are used to develop new contrast agents that can target the
specific molecular marker of the cells or can be activated to report on the physiological status or metabolic
activity of biological systems. In molecular imaging science, MR imaging has emerged as a leading technique
because it provides high-resolution three-dimension maps of the living subject. The future of molecular MR
imaging is promising as advancements in hardware, contrast agents, and image acquisition methods coalesce to
bring high resolution in vivo imaging to the biochemical sciences and to patient care. (Korean J Nucl Med 38(2):205-208, 2004) |
Keyword |
Molecular imaging, Magnetic resonance imaging, Contrast agents |
Full text Article |
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