다양한 배후 방사능 설정에 따른 Gates 법 사구체 여과율의 차이: I-125-Iothalamate 측정법과의 비교 (GFRs Measured by Gates' Method According to 5 Background Sites: Comparison with GFR Measured by I-125-Iothalamate Method) |
Author |
정현석.정용안.김성훈.김정호.이성용.손형선.백준현.정수교, |
Hyun Seok Jung, M.D., Yong An Chung, M.D., Sung Hoon Kim, M.D., Chung Ho Kim, M.D., Sung Young Lee, M.D., Hyung Seon Sohn, M.D., Jun Hyun Baik, M.D., Soo Kyo Chung, M.D. |
Affiliation |
가톨릭대학교 의과대학 방사선과학교실 Department of Radiology, The Catholic University of Korea, Seoul, Korea |
Abstract |
Purpose: The aim was to assess how the background site affects the Gates' glomerular filtration rate(GFR)
measurement using Tc-99m-DTPA in correlation with GFR by I-125-iothalamate method. Material and methods: The
study populations were 63 adults with 39 men and 24 women aged from 20 to 59 yrs (mean = 37.9 yrs). The
following five background regions of interest were used in measurement of GFR using Gates' method: 1) lower side
of each kidney(subrenal), 2) around each kidney(circumferential), 3) upper side of each kidney(suprarenal), 4) lateral
side of each kidney(lateral), 5) between the two kidneys(inter-renal). We also measured GFR using I-125-iothalamate
in each subject. The two studies were separated by 1 to 3 weeks. The subjects were divided into two groups by
renal depth. Group 1 with renal depth.7cm and group 2 with renal depth <7 cm. We calculated the means and
standard deviations of the GFRs measured by two studies. And we statistically analyzed the correlation and
differences among GFRs by Gates' method and the GFR by iothalamate method with correlation analysis. Results:
The GFRs by Gates' method using suprarenal and inter-renal background correction showed better correlation with
the GFR measured by I-125-iothalamate. And GFRs measured by Gates' method showed statistically significant
correlation with the GFR measured by I-125-iothalamate in the group with renal depth < 7cm. But GFRs measured
by Gates' method did not show statistically significant correlation with the GFR measured by I-125-iothalamate in
the group with renal depth .7cm. Conclusion: GFRs measured with Gates' method showed higher correlation
with the GFR measured by I-125-iothalamate when the regions of interest were placed over the suprarenal and
inter-renal backgrounds. And GFRs measured with Gates method showed statistically significant correlation with the
GFR measured by I-125-iothalamate in the group with renal depth < 7cm. (Korean J Nucl Med 38(4):306-310, 2004) |
Keyword |
Tc-99m-DTPA, I-125-Iothalamate, Background, Renal scintigraphy, Glomerular filtration rate, Renal depth |
Full text Article |
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