대한핵의학회지 (1967년~2009년)
대한핵의학회지 2004;38(5)344~346
Tc-99m DPD 골스캔과 복부 CT 영상에서 보이는 위암의 석회화
(Visualization of the Gastric Calcification due to Cancer on Tc-99m DPD and Abdominal CT Images)
Author 정영진,강도영,
Young-Jin Jeong, M.D., Do-Young Kang, M.D.
Affiliation 동아대학교 의과대학 핵의학교실
Department of Nuclear Medicine, Dong-A University College of Medicine, Busan, Korea
Abstract

A 69-year-old woman was presented with progressed dysphagia, gastric soreness and weight loss during 2 months. She was performed abdomen x-ray, EGDS and abdomen CT. Abdomen x-ray demonstrated punctuate calcification on LUQ. EGDS showed an ulceroinfiltrative mass with bleeding on cardia to antrum of stomach. And CT showed diffuse gastric wall thickness with multiple calcifications. Biopsy of the stomach and esophagus during EGDS examination revealed an adenocarcinoma, with signet ring cell type, infiltrating the wall of the stomach and the distal esophagus. Then Bone scan was performed a few days later. It revealed intense uptake in LUQ, corresponding to the calcium containing neoplasm seen on the abdomen x-ray, EGDS and abdomen CT. And there was no evidence of any metastatic lesion and thyroid uptake on the bone scan. There are many reports about accumulation of the tracer in extraosseous lesion, but only a few literatures were reported about gastric calcification in stomach cancer. More over, no reports showed CT images. We are performed many diagnostic examinations and found well correlation between them. The reason of gastric calcification is considered with calcium deposition within extracellular space due to hemorrhage or necrosis. Other possibility offered to explain gastric calcification have been increased blood flow and/or increased neovascularity with capillary leaks of tracer, and specific enzymatic (phosphatases) receptor binding of tracer. So, it was happened ion exchange between intracellular calcium and phosphate groups of tracer. (Korean J Nucl Med 38(5):344-346, 2004)

Keyword gastric calcification, gastric adenocarcinoma, Tc-99m DPD bone scan
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