소동물 영상을 위한 MicroPET R4 스캐너의 특성평가 (Performance Characteristics of MicroPET R4 Scanner for Small Animal Imaging) |
Author |
이병일.이재성.김진수.이동수.최창운1.임상무1, |
Byeong Il Lee, Ph.D., Jae Sung Lee, Ph.D., Jin Su Kim, M.S., Dong Soo Lee, M.D.,Chang Un Choi, M.D.1, Sang-Moo Lim, M.D.1 |
Affiliation |
서울대학교의과대학 핵의학교실, 원자력의학원1 Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea, Korea Institute of Radiology & Medical Sciences, Seoul, Korea1 |
Abstract |
Purpose: Dedicated animal PET is useful equipment for the study of new PET tracer. Recently, microPET R4 was
installed in the Korea institute of radiology and medical science. In this study, we measured the characteristics of
scanner. Materials and methods: Resolution was measured using a line source (F-18:65 μCi, inner diameter: 0.5
mm). The line source was put in the axial direction and was moved from the center of field of view to outside
with 1 mm interval. PET images were reconstructed using a filtered back-projection and ordered subset
expectation maximization. Line source (16.5 μCi, 78 mm) was put on the center of axial direction to measure the
sensitivity when the deadtime was under 1%. Images were acquired during 4 minutes respectively from center to
39 mm outward. Delayed count was subtracted from total count and then decay was corrected for the
calculation of sensitivity. Noise equivalent count ratio and scatter fraction were calculated using cylindrical
phantom. Results: Spatial resolution of reconstructed image using filtered back-projection was 1.86 mm(radial), 1.95
mm(tangential), 1.95 mm(axial) in the center of field of view, and 2.54 mm, 2.8 mm, 1.61 mm in 2 cm away from
the center respectively. Sensitivity was 2.36% at the center of transaxial field of view. Scatter fraction was 20%.
Maximal noise equivalent count ratio was 66.4 kcps at 242 kBq/mL. Small animal images were acquired for
confirmation of performance. Conclusion: Performance characteristics of microPET R4 were similar with reported
value. So this will be a useful tool for small animal imaging.(Korean J Nucl Med 39(1):49-56, 2005) |
Keyword |
MicroPET R4, Resolution, Sensitivity, Scatter fraction, Noise equivalent count ratio. |
Full text Article |
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