PET을 이용한 심근생존능의 평가 (Assessment of Myocardial Viability Using PET) |
Author |
윤석남, |
Seok-Nam Yoon, M.D |
Affiliation |
아주대학교 의과대학 핵의학교실 Department of Nuclear Medicine, College of Medicine, Ajou University, Suwon, Korea |
Abstract |
The potential for recovery of left ventricular dysfunction after myocardial revascularization represents a practical
clinical definition for myocardial viability. The evaluation of viable myocardium in patients with severe global left
ventricular dysfunction due to coronary artery disease and with regional dysfunction after acute myocardial
infarction is an important issue whether left ventricular dysfunction may be reversible or irreversible after therapy.
If the dysfunction is due to stunning or hibernation, functional improvement is observed. but stunned myocardium
may recover of dysfunction with no revascularization. Hibernation is chronic process due to chronic reduction in
the resting myocardial blood flow. There are two types of myocardial hibernation: "functional hibernation" with
preserved contractile reserve and "structural hibernation" without contractile reserve in segments with preserved
glucose metabolism. This review focus on the application of F-18 FDG and other radionuclides to evaluate
myocardial viability. In addition the factors influencing predictive value of FDG imaging for evaluating viability and
the different criteria for viability are also reviewed.(Korean J Nucl Med 39(2):133-140, 2005) |
Keyword |
Myocardial Viability, PET and F-18 FDG |
Full text Article |
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