대한핵의학회지 (1967년~2009년)
대한핵의학회지 2005;39(3)191~199
신장 방사선 섭취량 결정을 위한 Conjugate View 방법에 대한 평가
(Evaluation of a Conjugate View Method for Determination of Kidney Uptake)
Author 봉정균2·윤미진1,2·이종두1,2·김희중1,2·손혜경2·권윤영2·박해정1,2·김유선3,
Jung Kyun Bong, Ph.D.2, Mijin Yun, M.D.1,2, Jong Doo Lee, M.D. & Ph.D.1,2, Hee Joung Kim, Ph.D.1,2, Hye Kyung Son, M.S.2, Yun Young Kwon, B.S.2, Hae Jeong Park, Ph.D.1,2, Yu Seun Kim, M.D.3
Affiliation 연세대학교 핵의학과1, 진단방사선과 방사선의과학 연구소2, 외과학교실3
Division of Nuclear Medicine1, Research Institute of Radiological Science2, Department of Radiology, Department of Surgery3, Yonsei University College of Medicine, Yonsei University
Abstract

Purpose: In order to obtain better quantitation of kidney uptake, this study is to evaluate a conjugate view method (CVM) using a geometric mean attenuation correction for kidney uptake and to compare it to Gate's method. Materials & Methods: We used a Monte Carlo code, SIMIND and a Zubal phantom, to simulate kidney uptake. SIMIND was both simulated with or without scatter for the Zubal phantom. Also, a real phantom test was carried out using a dual-head gamma camera. The activity of 0.5 mCi was infused into two small cylinder phantoms of 5 cm diameter, and then, they were inserted into a cylinder phantom of 20 cm diameter. The results by the CVM method were compared with ideal data without both of attenuation and scatter and with Gate's method. The CVM was performed with or without scatter correction. The Gate's method was performed without scatter correction and it was evaluated with regards to 0.12 cm-1 and 0.15 cm-1 attenuation coefficients. Data were analyzed with comparisons of mean counts in the regions of interest (ROI), profiles drawn over kidney images and linear regression. Correlation coefficients were calculated with ideal data, as well. Results: In the case of the computer simulation, mean counts measured from ideal data, the CVM and the Gate's method were (right: 998¡¾209, left: 896¡¾249), (right: 911¡¾207, left: 815¡¾265), and (right: 1065¡¾267, left: 1546¡¾267), respectively. The ideal data showed good correlation with the CVM and the correlation coefficients of the CVM, Gate's method were (right: 0.91, left: 0.93) and (right: 0.85, left: 0.90), respectively. Conclusion: The conjugate view method using geometric mean attenuation correction resulted in better accuracy than the Gate's method. In conclusion, the conjugate view method independent of renal depths may provide more accurate kidney uptake.(Korean J Nucl Med 39(3):191-199, 2005)

Keyword Conjugate view method, geometric mean attenuation correction, scatter correction, kidney uptake,
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