종설 : 핵의학 영상과 추적자 동력학 분석법을 이용한 생체기능 정량화 (Quantitation of In-Vivo Physiological Function using Nuclear Medicine Imaging and Tracer Kinetic Analysis Methods) |
Author |
김수진1, 김경민2, 이재성1, |
Su Jin Kim, M.S.1, Kyeong Min Kim Ph.D.2, Jae Sung Lee Ph.D.1 |
Affiliation |
서울대학교 의과대학 핵의학교실1, 한국원자력의학원 방사선의학연구소 분자영상연구부2 1Department of Nuclear Medicine, College of Medicine, Seoul National University 2Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences |
Abstract |
Nuclear medicine imaging has an unique advantage of absolute quantitation of radioactivity concentration in body. Tracer kinetic analysis has been known as an useful investigation methods in quantitative study of in-vivo physiological function. The use of nuclear medicine imaging and kinetic analysis together can provide more useful and powerful intuition in understanding biochemical and molecular phenomena in body. There have been many development and improvement in kinetic analysis methodologies, but the conventional basic concept of kinetic analysis is still essential and required for further advanced study using new radiopharmaceuticals and hybrid molecular imaging techniques. In this paper, the basic theory of kinetic analysis and imaging techniques for suppressing noise were summarized. (Nucl Med Mol Imaging 2008;42(2):145-152) |
Keyword |
nuclear medicine imaging, tracer kinetic modeling, PET, SPECT |
Full text Article |
4202145152.pdf
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