대한핵의학회지 (1967년~2009년)
Nucl Med Mol Imaging 2008;42(6)488~490
항암치료 후에 병변의 크기는 감소하였으나 FDG 섭취는 증가한 비소세포폐암 환자 1예
(Significant Mismatch between FDG Uptake and Size after Chemotherapy in a Patient with Non-small Cell Lung Cancer)
Author 권성영, 정신영, 서영순, 하정민, 정아리, 오종률, 송호천, 민정준, 범희승,
Seong-Young Kwon, Shin-Young Jeong, Young-Soon Seo, Jung-Min Ha, Ari Chong, Jong-Ryool Oh, Ho-Chun Song, Jung-Joon Min, Hee-Seung Bom
Affiliation 전남대학교 의과대학 핵의학교실
Departments of Nuclear Medicine, Chonnam National University Medical School, Gwangju, Korea
Abstract

A 75-year-old man with non-small cell lung cancer (NSCLC) underwent F-18 fluorodeoxyglucose (FDG) PET/CT for staging. PET/CT showed distant metastases to intra-abdominal lymph nodes (LNs) as well as bilateral mediastinal LNs (stage IV). He underwent PET/CT (restaging PET/CT) 1 week after the completion of first-line chemotherapy (docetaxel + carboplatin). It showed markedly increased FDG uptake in primary tumor, whereas tumor size decreased significantly, compared to prior PET/CT. This lesion was aggravated on follow-up CT 3 months after the completion of chemotherapy. Although there are several reports that FDG PET has potential to evaluate early response to chemotherapy and prognosis, there are a few cases to show mismatch between FDG uptake and size on PET/CT. Thus we report a case of NSCLC showed increased FDG uptake of primary tumor while decreased tumor size on restaging PET/CT. (Nucl Med Mol Imaging 2008;42(6):488-490)

Keyword Non-small cell lung cancer, mismatch, FDG, size
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