대한핵의학회지 (1967년~2009년)
Nucl Med Mol Imaging 2009;43(5)386~394
게이트 심근 관류 SPECT에서 구한 심근 속도와 심근 관류를 중심으로 한 심근 기능 지표와의 비교연구
(Comparison Study between Myocardial Velocity obtained from Gated Myocardial SPECT and Myocardial Functional indices with a Focus on Myocardial Perfusion)
Author 하정민, 정신영, 범희승, 이병일,
Jung-Min Ha, M.D., Shin Young Jeong, M.D., Hee-Seung Bom, M.D., Ph.D., and Byeong-Il Lee, Ph.D
Affiliation 화순전남대학교병원 핵의학과
Department of Nuclear Medicine, Chonnam National Hawsun University Hospital, Hwasun, Jeonnam, Korea
Abstract

Purpose: We aimed to assess the myocardial velocity on gated myocardial perfusion SPECT (gated MPS), to compare myocardial velocity between patients without coronary artery disease (CAD) and CAD patients and to assess the correlation of myocardial velocity and perfusion and wall thickening on CAD group. Materials and Methods: Seventeen patients without CAD (M:F=9:8, mean age 61.8¡¾11.1 yrs: group A) and thirty-nine patients with CAD (M:F=18:21, mean age 66.9¡¾8.1 yrs : group B) had undergone one-day adenosine stress gated MPS. In twenty segment model, 12 segments (except apical and basal segments) of each patient were included. We obtained systolic and diastolic gate ratio in left ventricular volume curve by eight frames per cardiac cycle on gated MPS. Using the systolic and diastolic gate ratio and R-R time of each patient, we obtained systolic and diastolic time ratio. The myocardial velocity was defined as wall thickening over systolic or diastolic time. Results: We presented normal range of myocardial velocities according segments and territories of coronary artery. The myocardial velocity of group B was significantly lower than group A (p=0.00). There was no significant difference between the myocardial velocity of group B with preserved EF and group A. The stress systolic velocity significantly correlated with regional myocardial perfusion in group B with preserved EF (p=0.00) as well as decreased EF (p=0.01). In group B, stress perfusion of segments which had decreased wall thickening and decreased myocardial velocity was significantly lower than segments which had decreased wall thickening and preserved myocardial velocity (p=0.01). Conclusion: The new functional index of velocity will be used as an useful of gated MPS.

Keyword Gated MPS, myocardial velocity, perfusion, wall motion, functional index
Full text Article 03_하정민.pdf 03_하정민.pdf
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