Brain Perfusion SPECT

• Hypoperfusion in bilateral F-P-O, P, P-T-O, F-P-T, and bi- or unilateral BG in acute CO poisoning

• Hypopefusion in frontal and temporal lobe :

? cognitive impairment and/or affective change

• Diffuse patchy hypoperfusion throughout the cerebral cortex.

  • good correlation between the findings of SPECT and the outcome of delayed CO sequelae.

• Bilateral mediofrontal hypoactivity :

  • specifically associated with three clinical signs: motor disabilities predominating in the lower limbs, urinary incontinence, and akinetic mutism.