There have been reported numberous cases of liver scanning in use of 198Au colloid by many investigators, however, one in use of 113mIn colloid has not been reported as yet in this country. The dose of 113mIn for high diagnostic value in examination of each organ was determined and the diagnostic interpretability of liver scanning with the use of 113mIn was carefully evaluated in comparison with the results of the liver scanning by the conventionally applied radioisotope. The comparative study of both figures of liver scanning with the use of 113mIn colloid and 198Au colloid delivered following results:1) The liver uptake rate and clearance into peripheral blood were accentuated more in case of 113mIn colloid than in case of 198Au colloid. 2) The interpretability of space occupying lesion in liver scanning with 113mIn was also superior to one with 198Au. 3) The figure of liver scanning with 113mIn colloid corresponds not always to the figure with 198Au. This difference can be explained by difference of phagocytic ability of reticuloendotherial system within liver. 4) In the liver scanning with 113mIn colloid, the spleen is also visualized even in normal examine. 5) In the cases of disturbed liver function, uptake is more decreased in use of 113mIn colloid than in 198Au, in the spleen, however, the way is contrary. 6) With use of 113mIn colloid, the time required for scanning could be shortened in comparison with 198Au. 7) The filtration of 113mIn colloid for scanning prior to human administration gives an expectation for better scanning figure.