항갑상선제로 치료받은 Graves 병 환자에서 수술시 갑상선 정맥혈과 말초정맥혈간에 TSH 수용체항체의 활성도에는 차이가 없다 ( There is no Gradient of TSH Receptor Antibody Activity Between Thyroidal and Peripheral Venous Blood in Patients with Graves` Disease () |
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고창순(Chang Soon Koh),이명철(Myung Chul Lee),조보연(Bo Youn Cho),송영기(Young Kee Shong),궁성수(Sung Soo Koong),오승근(Seung Keun Oh),이명혜(Myung Hae Lee), |
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Abstract |
Thyrotropin binding inhibitory immunoglobulin (TBII) and thyroid stimulating antibody (TSAb) activities were measured in the thyroidal and peripheral venous blood samples at the time of subtotal thyroidectomy from twenty one patients with Graves' disease prepared for surgery with antithyroid drugs. There was no difference in TBII and TSAb activities between thyroidal and peripheral blood samples. These findings were regarded that while intrathyroidal lymphocytes are major site of thyrotropin receptor antibody (TRAb) production, similar levels are found in thyroidal and peripheral veins and that this in vive study cannot exactly ascertain the TRAb producing site. |
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28500848.pdf
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