원저 : 휴식 Tl - 201 / 부하 Tc - 99m MIBI 심근 SPECT의 관상동맥질환 진단 정확성 ( Diagnostic Accuracy of Rest Tl - 201 / Stress Tc - 99m - MIBI Myocardial SPECT in the Diagnosis of Coronary Artery Disease ) () |
Author |
여정석(Jeong Seok Yeo),이동수(Dong Soo Lee),강건욱(Keon Wook Kang),손대원(Dae Won Sohn),오병희(Byung Hee Oh),이명묵(Myung Mook Lee),정준기(June Key Chung),박영배(Young Bae Park),이명철(Myung Chul Lee),서정돈(Jung Don Seo),이영우(Young Woo Lee),고창순(Chang Soon Koh), |
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Affiliation |
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Abstract |
Objective: Standard stress/rest Tc-99m MIBI and T1-201
myocardial perfusion study have some limitations such
as stress/rest image overlap for Tc-99m-MIBI, low
energy for T1-201 and long period of study time for two
separate studies. Separate acquisition rest T1-
20l/stress Tc-99m MIBI dual isotope study is a
potentially efficient myocardial perfusion imaging
protocol that combines the high resolution of Tc-99m
for stress perfusion assessment and T1-201 for
viability assessment. This study assessed the
usefulness and diagnostic accuracy for this new
approach. Methods: We tried to evaluate sensitivity and
specificity of dual isotope separate acquisition
protocol in 67 patients. Immediately after resting T1-
201 SPECT data was acquired, dipyridamole stress Tc-99m
MIBI myocardial perfusion study was performed. Visual
analysis was carried out qualitatively with 0 to 3
scoring system for 17 segments of left ventricle in the
reconstructed horizontal long axis and short axis
slices. Results: Total study was complete within 3
hours. In angiographic correlation, dual isotope SPECT
demonstrated high sensitivity(85%) and in a small group
of patients, high specificity was also obseved (100%).
Conclusion: Combined thallium- 20l/stress Tc-99m MIBI
SPECT displayed similiar diagnostic accuracy to
protocol using stress/rest Tc-99m MTBI SPECT. This
protocol was completed in shorter period than the
previous protocols and therefore enhance laboratory
throughput and patients convenience. |
Keyword |
Diagnostic accuracy, Dual isotope separate acquisition, Coronary artery disease |
Full text Article |
28501629.pdf
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