원저 : 기저 / 아세타졸아미드 부하 연속 촬영 뇌관류 SPECT 최적화 ( Optimization of Subtraction Brain Perfusion SPECT with Basal / Acetazolamide Consecutive Acquisition ) () |
Author |
이동수(Dong Soo Lee),이태훈(Tae Hoon Lee),김경민(Kyeong Min Kim),정준기(Jung Key Chung),이명철(Myung Chul Lee),고창순(Chang Soon Koh), |
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Affiliation |
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Abstract |
This study investigated the method to adjust
acquisition time(a) and injection dose(i) to make the
best basal and subtraction images in consecutive SPECT.
Image quality was assumed to be mainly affected by
signal to noise ratio(S/N). Basal image was subtracted
from the second image consecutively acquired at the
same position. We calculated S/N ratio in basal SPECT
images(S1/N1) and subtraction SPECT images(Ss/Ns) to
find a(time) and i(dose) to maximize S/N of both images
at the same time. From phantom images, we drew the
relation of image counts and a(time) and i(dose) in our
system using fanbeam-high-resolution collimated triple
head SPECT. Noise by imaging process depended on
Poisson distribution. We took maximum tolerable
duration of consecutive acquisition as 30 minutes and
maximum injectible dose as 1,850MBq(50 mCi)(sum of two
injections) per study. Counts of second-acquired
image(S2), counts(Ss) and noise(Ns) of subtraction
SPECT were as follows. C1 was the coefficient of
measurement with our system. |
Keyword |
Subtraction SPECT, Optimization, Rest/acetazolamide study, Signal to noise ratio |
Full text Article |
28502015.pdf
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