원저 : 디피리다몰 심근관류 SPECT 를 이용한 관동맥질환 진단에 있어 남녀간의 진단율 비교 ( Gender Difference of Accuracy in Detecting Coronary Artery Disease by Myocardial Perfusion SPECT ) () |
Author |
민정준(Jung Jun Min),범희승(Hee Seung Bom),송호천(Ho Cheon Song),정환정(Hwan Jeong Jeong),김지열(Ji Yeul Kim), |
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Affiliation |
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Abstract |
Purpose: Myocardial SPECT is an effective test for
detecting coronary artery disease in the general
population. But the diagnostic accuracy between sexes
is not defined. The purpose of this study is to compare
the diagnostic accuracy between males and females.
Materials and Methods: One hundred and seventy seven
male and 98 female patients who underwent myocardial
SPECT within 1 month of coronary angiography were
studied. Myocardial SPECTs were considered abnormal if
fixed or reversible perfusion defects were detected.
Stenosis severity of ≥ 50% luminal diameter reduction
of any artery defined coronary artery disease (CAD).
Results: Overall sensitivity for detection of CAD was
98% in men and 97% in women (p=not significant).
However, specificities, accuracies, and positive
predictive values (PPV) in men and women were 49% vs
31% (p〈0.05), 81% vs 57% (p〈0.01), 78% vs 48% (P
〈0.01), respectively Diagnostic accuracies for
detection of right coronary artery disease were not
different in both sexes, however, accuracies for
detection of left anterior descending artery disease
and left circumflex artery disease were significantly
lower in female (p〈0.05). Conclusion: A significant
difference of diagnostic accuracy between sexes,
especially in LAD and LCx disease, was noted. Artifacts
from breast attenuation might be a cause for the lower
diagnostic accuracy in female. |
Keyword |
99mTc-tetrofosmin, 99mTc-MIBI, Myocardial SPECT, Coronary artery disease, Gender difference, Soft tissue attenuation |
Full text Article |
28502126.pdf
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