3 차원 데이터획득 뇌 FDG-PET 의 정확도 평가 ( An Assessment of the Accuracy of 3 Dimensional Acquisitionin F-18 fluorodeoxyglucose Brain PET Imaging ) () |
Author |
이정림(Jeong Rim Lee),최용(Yong Choi),김상은(Sang Eun Kim),이경한(Kyung Han Lee),김병태(Byung-Tae Kim),최창운(Chang Woon Choi),임상무(Sang Moo Lim),홍성운(Seong Wun Hong), |
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Affiliation |
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Abstract |
Purpose: To assess the quantitative accuracy and the
clinical utility of 3D volumetric PET imaging with FDG
in brain studies, 24 patients with various neurological
disorders were studied. Materials and Methods: Each
patient was injected with 370 MBq of 2-[18F]fluoro-2-
deoxy-D-glucose. After a 30 min uptake period, the
patients were imaged for 30 min in 2 dimensional
acquisition (2D) and subsequently for 10 min in 3
dimensional acquisition imaging (3D) using a GE
AdvanceTM PET system. The scatter corrected 3D (3D SC)
and non scatter-corrected 3D images were compared with
2D images by applying ROIs on gray and white matter,
lesion and contralateral normal areas. Measured and
calculated attenuation correction methods for emission
images were compared to get the maximum advantage of
high sensitivity of 3D acquisition. Results: When
normalized to the contrast of 2D images, the contrasts
of gray to white matter were 0.75¡¾0.13 (3D) and
0.95¡¾0.12 (3D SC). The contrasts of normal area to
lesion were 0.83¡¾0.05 (3D) and 0.96¡¾0.05 (3D SC).
Three nuclear medicine physicians judged 3D SC images
to be superior to the 2D with regards to resolution and
noise. Regional counts of calculated attenuation
correction was not significantly different to that of
measured attenuation correction. Conclusion: 3D PET
images with the scatter correction in FDG brain studies
provide quantitatively and qualitatively similar images
to 2D and can be utilized in a routine clinical setting
to reduce scanning time and patient motion artifacts.
(Korean J Nucl Med 1999;33:327-36) |
Keyword |
Positron emission tomography, F-18 fluorodeoxyglucose, 3 dimensional acquisition |
Full text Article |
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