원저 / 핵의학 영상의 정량적 분석을 통한 신장기능 평가 프로그램 개발 ( Development of Program for Renal Function Study with Quantification Analysis of Nuclear Medicine Image ) () |
Author |
송주영(Ju Young Song),이형구(Hyoung Koo Lee),서태석(Tae Suk Suh),최보영(Bo Young Choe),신경섭(Kyung Sub Shin),정용안(Yong An Chung),김성훈(Sung Hoon Kim),정수교(Soo Kyo Chung), |
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Abstract |
Purpose: In this study, we developed a new software tool for the analysis of renal scintigraphy which can be modified more easily by a user who needs to study new clinical applications, and the appropriateness of the results from our program was studied. Materials and Methods: The analysis tool was programmed with IDL5.2 and designed for use on a personal computer running Windows. For testing the developed tool and studying the appropriateness of the calculated glomerular filtration rate (GFR), 99mTc-DTPA was administered to 10 adults in normal condition. In order to study the appropriateness of the calculated mean transit time (MTT), 99mTc-DTPA and 99mTc-MAG3 were administered to 11 adults in normal condition and 22 kidneys were analyzed. All the images were acquired with ORBITOR, the Siemens gamma camera. Results: With the developed tool, we could show dynamic renal images and time activity curve (TAC) in each ROI and calculate clinical parameters of renal function. The results calculated by the developed tool were not different statistically from the results obtained by the Siemens application program (Tmax: p=0.68, Relative Renal Function: p=1.0, GFR: p=0.25) and the developed program proved reasonable. The MTT calculation tool proved to be reasonable by the evaluation of the influence of hydration status on MTT. Conclusion: We have obtained reasonable clinical parameters for the evaluation of renal function with the software tool developed in this study. The developed tool could prove more practical than conventional, commercial programs. (Korean J Nucl Med 2001;35:89-99) |
Keyword |
99mTc-DTPA, 99mTc-MAG3, Gamma camera, Renal function, Time activity curve, Glomerular filtration rate, Mean transit time. |
Full text Article |
28503315.pdf
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