정량적 게이트 심근관류 SPECT (Quantitative gated myocardial perfusion SPECT) |
Author |
안병철, |
Byeong-Cheol Ahn, MD. PhD. |
Affiliation |
경북대학교 의과대학, 핵의학 교실 Department of Nuclear Medicine, Kyungpook National University Hospital, Daegu, Korea. |
Abstract |
Myocardial perfusion imaging has been increasingly used to provide prognostic data and guidance on the
choice of appropriate management of patients with known or suspected coronary artery disease. The
electrocardiogram gated myocardial SPECT program is coming into wide use with an advent of
99mTc-labeled tracers and an improvement of SPECT machines. The gated technique permits measurement
of important cardiac prognostic indicators without any further discomforts or radiation burden in patients
underwent standard myocardial perfusion SPECT. In addition, gated study significantly improves diagnostic
yield by reducing the number of borderline interpretations and could find myocardial stunning and viable
myocardium. Gated single photon emission computed tomography (SPECT) imaging allows the automated
calculation of end-diastolic volume, end-systolic volume, ejection fraction, myocardial mass and the
assessment of regional wall motion and thickening, and it have dramatically improved assessment of
coronary artery disease in routine nuclear practice. This allows the simultaneous assessment of both
perfusion and function within the same acquisition, and serves as a cost-effective technique for providing
more diagnostic data with fewer diagnostic tests. Because the diagnostic and prognostic power derived from
knowledge of left ventricular function can be added to that provided by assessing myocardial perfusion,
gated SPECT imaging has rapidly gained widespread acceptance and is now used on a routine clinical
basis in a growing number of laboratories, including South Korea. The gated SPECT technique for
measurement of left ventricular parameters has been validated against a variety of well established
techniques.
In this work, overview of gated myocardial perfusion SPECT focus on functional parameters is presented. |
Keyword |
Gated SPECT, Myocardial perfusion, Functional parameter, Quantification |
Full text Article |
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