분자핵의학영상 개관 (General Perspectives for Molecular Nuclear Imaging) |
Author |
정준기, |
June-Key Chung, M.D. |
Affiliation |
서울대학교 의과대학 핵의학교실, 암연구소 분자영상치료연구실 Department of Nuclear Medicine, Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea |
Abstract |
Molecular imaging provides a visualization of normal as well as abnormal cellular processes at a molecular or
genetic level rather than at a anatomical level. Conventional medical imaging methods utilize the imaging signals
produced by nonspecific physico-chemical interaction. However, molecular imaging methods utilize the imaging
signals derived from specific cellular or molecular events. Because molecular and genetic changes precede
anatomical change in the course of disease development, molecular imaging can detect early events in disease
progression. In the near future, through molecular imaging we can understand basic mechanisms of disease, and
diagnose earlier and, subsequently, treat earlier intractable diseases such as cancer, neuro-degenerative diseases,
and immunologic disorders. In beginning period, nuclear medicine started as a molecular imaging, and has had a
leading role in the field of molecular imaging. But recently molecular imaging has been rapidly developed. Besides
nuclear imaging, molecular imaging methods such as optical imaging, magnetic resonance imaging are emerging.
Each imaging modalities have their advantages and weaknesses. The opportunities from molecular imaging look
bright. We should try nuclear medicine continues to have a leading role in molecular imaging. (Korean J Nucl Med 38(2):111-114, 2004) |
Keyword |
Nuclear medicine, Molecular imaging, Optical imaging, MR imaging, Reporter gene |
Full text Article |
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