분자영상 방사성추적자의 생산에 사용되는 방사성동위원소 표지방법 (Radiolabeling Methods Used for Preparation of Molecular Probes) |
Author |
최연성, |
Yearn Seong Choe, Ph.D. |
Affiliation |
성균관대학교 의과대학 삼성서울병원 핵의학과 Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
Abstract |
Molecular imaging visualizes cellular processes at a molecular or genetic level in living subjects, and diverse
molecular probes are used for this purpose. Radiolabeling methods as well as radioisotopes are very important in
preparation of molecular probes, because they can affect the biodistribution in tissues and the excretion route. In
this review, the molecular probes are divided into small organic molecules and macromolecules such as peptides
and proteins, and their commonly used radiolabeling methods are described. (Korean J Nucl Med 38(2):121-130, 2004) |
Keyword |
Molecular probe, Radioisotope, Radiolabeling method, Small organic molecules, Proteins, Peptides, PET,SPECT |
Full text Article |
3802121.pdf
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